منابع مشابه
Variation in secretor and Lewis type frequencies within the British Isles.
A study of the ABO groups and secretor status of alcoholic patients which included individuals of English, Irish, and Scottish origin necessitated a comparison with appropriate normal controls (Camps, Dodd, and Lincoln, 1969). Although the figures most quoted for secretor/ non-secretor frequencies in the British Isles are those of McConnell (Race and Sanger, 1968), which show a non-secretor fre...
متن کاملMetabolic and immunologic consequences of ABH secretor and Lewis subtype status.
Determining ABH secretor phenotype and/or Lewis (Le) blood group status can be useful to the metabolically-oriented clinician. For example, differences in ABH secretor status drastically alter the carbohydrates present in body fluids and secretions; this can have profound influence on microbial attachment and persistence. Lewis typing is one genetic marker which might help identify subpopulatio...
متن کاملLewis phenotype, secretor status, and coeliac disease.
Patients who cannot secrete ABO and Lewis blood group antigens into body fluids, an ability controlled by a single gene on chromosome 19, are known to be at increased risk of certain autoimmune diseases associated with human leucocyte antigen (HLA) markers. This study investigated the possibility of an association with coeliac disease using red cell Lewis (Le) blood group phenotype to infer sec...
متن کاملABH and Lewis blood group expression in colorectal carcinoma.
The expression of ABO(H) and Lewis blood group antigens on 68 colorectal carcinomas from 63 patients was studied by immunohistochemical staining of tissue specimens. The pattern of antigen expression was as follows: ABH was expressed in normal tissue only in secretors and was expressed in the proximal but not distal colon. In tumors, there was net loss of ABH expression in the proximal and net ...
متن کاملExpression of the gene encoding secretor type galactoside 2 α fucosyltransferase (FUT2) and ABH antigens in patients with oral lesions
OBJECTIVE The aim of this work was to evaluate the expression of FUT2 gene in saliva and histo ABH antigens of patients with oral lesions. STUDY DESIGN In total 178 subjects were examined, half of whom suffered from oral pre-cancerous and cancerous lesions, while the other half were the healthy control group We analyzed the FUT 2 polymorphism by ASO-PCR (allele specific oligonucleotid - polym...
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ژورنال
عنوان ژورنال: Journal of Medical Genetics
سال: 1972
ISSN: 1468-6244
DOI: 10.1136/jmg.9.1.46